Bone is the stent of the human body, participates in the metabolism of the whole body, and is an important part of the human movement system. However, due to the influence of diseases, aging, frequent traffic accidents and other factors, the number of bone injury cases is increasing year by year, so the demand for bone substitute materials is increasing. In recent years, bone substitute materials represented by hydroxyapatite and hydroxyapatite coating have gradually become the darling of clinical applications.

Specification of nano hydroxyapatite powder:
Purity:99.9%

CAS No:1306-06-5

ENINEC No.:215-145-7

Appearance:white powder

SSA:50m2/g

Shape: spherical

Characteristics and preparation methods of nano hydroxyapatite

Nano hydroxyapatite is a new type of inorganic ceramic material with unique biological activity. It overcomes the characteristics of traditional hydroxyapatite, such as hard plasticity, brittleness, and slow degradation. It has high chemical activity and is beneficial to increase The biological activity of the material and the increased surface area are conducive to cell attachment and growth.

The ability of nano-hydroxyapatite to induce new bone formation is unmatched by other materials. At present, the preparation methods mostly adopt hydrothermal method, precipitation method, supersynthetic method, sol-gel method, microemulsion method and liquid-solid synthesis method. And other chemical synthesis methods.

Application of nano hydroxyapatite

As we all know, hydroxyapatite is one of the natural components of bones. Because of its strong corrosion resistance, strong bone induction, and its degradability in the body, it is widely used in human bone bionic regeneration materials and hydroxyapatite coatings. It is currently one of the most widely studied materials in the field of bone repair.
However, existing research results show that although pure hydroxyapatite has excellent biocompatibility and biological activity, it has poor mechanical properties and cannot be used as a load-bearing implant material. The other kind of bone substitute materials, medical titanium and titanium alloy materials, although they have excellent mechanical properties, have poor wear resistance and are biologically inert materials. The combination with bone is a mechanical lock.

In view of this, the preparation of hydroxyapatite bioceramic coatings on the surface of medical titanium and titanium alloys is currently a research hotspot at home and abroad, and has important theoretical and practical significance.

With titanium alloy as the substrate, the hydroxyapatite coating prepared by plasma spraying technology has a high bonding strength between the coating and the substrate. After the material is implanted in the human body, the titanium alloy can provide sufficient mechanical strength. The hydroxyapatite coating on the surface The layer is easy to combine with human bones, and induces the formation of new bones on the surface of human bones. Generally, it can induce the formation of new bones within a few months. However, the phenomenon of coating shedding after implantation in the body needs further study.

Concluding remarks

Nano-sized hydroxyapatite has stable performance under physiological environment, which can provide good support for the adhesion and growth of bone cells, make bone cells easy to attach, secrete a variety of osteogenic differentiation factors, and in the process of bone cell calcification, Nano hydroxyapatite also provides crystal nuclei for calcification of bone cells to develop bone conduction. SAT NANO is one of the best supplier of hydroxyapatite in China, if you have any interest, please feel free to contact us at admin@satnano.com